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Treatment of intradural extramedullary myxopapillary ependymoma of lumbar spine: A rare case report and literature review

摘要


Herein, we reported a 59-year-old woman presenting with lumbago, paresthesia and weakness of both lower limbs. Magnetic resonance imaging (MRI) study showed a large intradural extramedullary spinal tumor with adjacent bony erosion at L1 and L2 levels. The patient underwent gross total resection (GTR) of the tumor to decompression the symptoms and neurologic deficits. Histopathological analysis was consistent with myxopapillary ependymoma, World Health Organization (WHO) grade I. Intradural extramedullary spinal myxopapillary ependymomas (MPE) are extremely rare. This lesion is optimally assessed with MRI and determining the location of the lesion will imply the diagnostic considerations to varieties of tumor entities. The similarities in morphology among metastatic carcinoma, chordoma, and myxopapillary ependymoma, diagnosis should be made in conjunction with clinical history including tumor location, radiological findings, histology, and immunohistochemical profile. The best treatment for this lesion is GTR and adjunctive radiotherapy is necessary in cases of recurrence and malignant transformation.

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