Lymphomatoid Granulomatosis on F-18 FDG PET/CT

淋巴瘤樣肉芽腫在氟-18 FDG正子造影表現

丁建鑫(Chien-Hsin Ting) ； 朱任公(Yum-Kung Chu)

《核子醫學暨分子影像雜誌》 28卷3期 (2015/09) Pp. 132-135

https://doi.org/10.6332/ANMMI.2803.006

摘要

淋巴瘤樣肉芽腫是一種人類皰疹病毒陽性之大B細胞淋巴瘤，病變常見於淋巴結外，影響範圍包括肺部、腎臟、肝臟、腦部及皮膚。本文報告一位86歲男性病人，因發燒及咳嗽而住院，於皮膚上發現數個紅斑狀結節。稍後做了病理切片檢查，病理報告顯示為淋巴瘤樣肉芽腫。他接受rituximab治療，為了追蹤疾病進程，病人並且接受了數次正子掃描。正子掃描顯示治療初始反應良好，但於治療結束三個月後，病情惡化急劇復發，病灶廣布於軀幹及肺部。一般來說對典型淋巴瘤，正子掃描是一個很好的監測工具，但在淋巴瘤樣肉芽腫的急劇過程中，正子掃描在評估本症的角色尚未清楚。

關鍵字

氟-18 FDG ； 淋巴瘤樣肉芽腫 ； 正子造影

並列摘要

Lymphomatoid granulomatosis is an Epstein- Barr virus-positive large B cell lymphoma. Extranodal disease is common, involving the lung, kidney, liver, brain, and skin. We present a case of an 86-year-old male who was admitted due to fever and cough. Several reddish nodules were noted on the skin and biopsy was done. The pathological findings revealed lymphomatoid granulomatosis. He received rituximab for treatment. A sequence Serial examination of PET/CT was done as disease staging and treatment monitoring during the course of the disease, displaying an initial remission achieved after the treatment, but a dramatic relapse shortly afterwards. It is obvious that the surveillance in our case is insufficient merely according to the results of FDG PET/CT. Although PET/CT is an excellent tool for disease surveillance in classical lymphoma, but its role in lymphomatoid granulomatosis is unclear.

並列關鍵字

F-18 FDG ； lymphomatoid granulomatosis ； PET/CT