Due the limitation of worldwide environmental regulations to sulfur content in oil is increasingly stringent, there are two main technologies: catalytic and non-catalytic hydrodesulfurization are used for desulfurization. In terms of CPC Coporation Taiwan Refining & Manufacturing Research Institute this article introduces the theory and current research ststus of catalytic hydrodesulfurization and oxidative desulfurization, which belongs to non-catalytic hydrodesulfurization. Meanwhile the advantages and disadvantages of two desulfurization technologies are also compared in this text.