DNA cryptography is a new promising direction in cryptography research that emerged with the evolution in DNA computing field. DNA can be used not only to store and transmit the information, but also to perform computation. Although in its primitive stage, DNA cryptography is shown to be very effective. In this the concept of DNA is being used in the encryption and decryption process. This also proposes a unique cipher text generation procedure as well as a new key generation procedure. This proposal wants to design a method which contains two rounds. For each round, we secretly select a reference DNA sequence and a secret Key (SK). In the first round process, generate a secured symmetric, a secretly selected DNA sequence S and cipher block chaining mode(CBC)- a Conventional cryptography technique which generate a intermediate form of cipher text and in the second round process, the intermediate form of cipher text converted into final cipher text(S) using a reference DNA Sequences and convert this into faked DNA Sequence called human made DNA Sequence(S') so it will become a more complicated for intruder to extract original message from faked DNA Sequence(S') send this faked DNA Sequence to the receiver together with many other DNA, or DNA-like sequences to the receiver.