Epidemiological Survey of Hyperuricemia in Urban Chinese

高尿酸血症在台北市雙園與北投地區之流行病學之調查

黃政典(Chien-Tien Huang)

《中華公共衛生雜誌》 14卷3期 (1995/06) Pp. 220-227

https://doi.org/10.6288/CJPH1995-14-03-02

摘要

為了要瞭解台灣地區都市居民高尿酸血症的情形，吾人於台北市雙園區與北投區隨機調查其居民，抽血檢查其血清尿酸值之分佈情形。本研究發現：雙園區共1383名：其中男為592名、女為791名血清尿酸平均值：男為5.82±0.09mg/dl、女為4.22±0.05mg/dl。其中高尿酸血症，男佔16.2%、女佔11.2%。北投區共1540名，其中男為628名、女為912名。血清尿酸平均值：男為6.07±0.07mg/dl、女為4.70±0.05mg/dl。其中高尿酸血症，男佔19.3%、女佔17.8%。兩區之間，女性居民血清尿酸值有明顯差異、男性則無。男女兩性年齡超過70歲組，血清尿酸值都高於其它年齡組別。北投區居民中，男性教育程度在國中及大專以上的高尿酸血症罹患率較高。女性則以無教育者較高。依職業來分，男性並無高尿酸血症罹患率之差異，女性則有明顯差異，以無職業者最高。造成此男女間之差異，其原因尚不清楚，因此建議更進一步對特定族群血清尿酸檢測，以確立不同職業及教育程度與高尿酸血症之關係。

關鍵字

中國人 ； 高尿酸血症 ； 流行病學

並列摘要

In order to gain a better understanding of the prevalence of hyperuricemia in Urban Chinese people as well as to examine the association of hyperuricemia with sociodemographic fuctors, we compared the serum levels of uric acid in Shuangyuan and Peitou residents of Taipei City. A random sample of 1383 (592 male and 791 female) residents of the Shuangyuan precinct of southern Taipei City and 1540 (628 male and 912 female) residents of the Peitou precinct of northern Taipei City were included in the 1985 study. The level of serum uric acid was determined by autoanalyzer using an enzymatic method. The results of serum uric acid were 5.82±0.09 mg/dl for males and 4.22±9.05 for female from Shuangyuan, and 6.07±9.07 mg/dl for males and 4.07±9.05 mg/dl for females trom Peitou, and 5.95±0.06 for males and 4.48±0.04 for females together. The age-adjusted prevalence of hyperuricemia, defined as a serum uric acid＞7.5 mg/dl for males and serum uric acid＞6.0 mg/dl for females, was 17.8 percent for males and 12.4 for females together; 16.2 (raw 15.9 percent) for male and 11.2 percent (raw 9.5 percent) for female Shuangyuan residents; 19.3 percent (raw 19.6 percent) for male and 17.8 percent (raw 25.0 percent) for female Peitou residents, with a significantly in Peitou females and also the total prevalence, but not in the male subgroup. The mean level of serum uric acid was found to increase with age over 70 for males and over 50 for females in these two areas of Taipei city. Further studies aimed at certain specified groups are needed to further reveal the relationship of sociodemographic factors and hyperuricemia.

並列關鍵字

Chinese ； epidemiology ； gout ； hyperuricemia