非胰島素依賴型糖尿病病人死亡狀況及預後因子

本文收集已發表有關非胰島素依賴型糖尿病(non-insulin-dependent diabetes mellitus, NIDDM)病人死亡率以及預後因子的文獻，綜述整合以往研究結果。糖尿病病人死亡率較一般人增加的理由尚不是很清楚。在台灣，有關引起非胰島素依賴型糖尿病病人死亡率及預測因子的研究仍非常少。文獻顯示，NIDDM病人的死亡率是一般人口的2-6倍。越年輕其增加的死亡率越高。非胰島素依賴型糖病病人的主要死亡原因是心血管疾病、糖尿病、腦血管疾病、腎臟病變、惡性腫瘤。首次診斷為糖尿病的年齡、空腹血糖、高膽固醇血症、高血壓、蛋白尿、肥胖是非胰島素依賴型糖尿病病人死亡率的預後因子。台灣地區自1993年以來，糖尿病已躍居台灣地區十大死亡原因的第五位。它是慢性病死亡原因中增加人數最快的疾病。雖然NIDDM病人的預後因人而異，不過對於NIDDM病程的瞭解不僅可以改善病人的健康，也可以作為NIDDM治療策略的基礎，減少NIDDM病人死亡率。

關鍵字

非胰島素依賴型糖尿病；死亡率；預後因子

並列摘要

Research on mortality and prognostic factors of non-insulin-dependent diabetes mellitus (NIDDM) were reviewed in detail. The reasons for the excess mortality in diabetes remain ill-defined at present. It is not clear to what extent this excess is attributable to an increased prevalence or force of established risk factors for morbidity and mortality in non-diabetic populations and to what extent specifically diabetes related-factors may play a role. Few studies have examined their relationship between risk factors and mortality in people with NIDDM in Taiwan. There are 2-6 times excess mortality in people with NIDDM compare with the general population. The excess mortality was greater among young adults and lowest among elderly. Death from cardiovascular disease, diabetes, cerebrovascular disease, nephropathy, and cancer account for the larger proportion of this excess. Age at initial diagnosis, fasting blood sugar, hypercholesterolemia, hypertension, proteinuria, obesity were the main prognostic factors for the mortality of NIDDM. Since 1993, diabetes is the fifth leading cause of death in Taiwan. It is the chronic disease with marked increasing rate of death numbers in Taiwan. A major challenge in diabetes management is reducing unfavorable risk factors to ameliorate the high rates of morbidity and mortality.

並列關鍵字

non-insulin-dependent diabetes mellitus ； mortality ； prognostic factors

國際替代計量

非胰島素依賴型糖尿病病人死亡狀況及預後因子

全文下載

主題瀏覽