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Predictors of 6-Month Angiographic Restenosis inside Bare-Metal Stent in Chinese Patients with Coronary Artery Disease

並列摘要


Background: Bare-metal stents are widely used in Chinese population with coronary artery disease. Many reports of predictors of in-stent restenosis (ISR) are available from trials mainly conducted in the Western population. However, predictors of ISR in Chinese population are rarely described. Methods: This study enrolled 609 patients who had procedural success of coronary stenting with bare-metal stents and 6-month angiographic follow-up from January 1998 to December 2000 in our hospital. The baseline characteristics, angiographic and procedural parameters of these patients were collected into our database. The definition of ISR was more than 50% stenosis at the intervention site. Results: Two hundred and fifty-one patients (41.2%) had ISR and 358 patients without ISR. By univariate analysis, the predictors of ISR were diabetes mellitus, multi-vessel disease, left anterior descending artery lesion, complex lesion, small vessel and stent sizes, long stent and lesion lengths and small post-procedure minimal luminal diameter. By multivariate analysis, the independent predictors of ISR were post-procedure minimal luminal diameter (OR: 1.969, 95% CI: 1.435-2.703; p<0.001), diabetes mellitus (OR: 1.831, 95% CI: 1.274-2.633; p=0.001), complex lesion (OR: 1.827, 95% CI: 1.040-3.209; p=0.036), and left anterior descending artery involvement (OR: 1.498, 95% CI: 1.032-2.173; p=0.033). Conclusion: In this study, post-procedure minimal luminal diameter, presence of diabetes mellitus, complex lesions and left anterior descending artery involvement are predictive of 6-month angiographic restenosis inside bare-metal stents in Chinese population.

並列關鍵字

Stent Restenosis Coronary artery disease

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