- 期刊
Leukoencephalopathy after Levamisole for the Treatment of Verrucae
並列摘要
Purpose: Levamisole is an antihelmintic and immunomodulator used as a dewormer and in combination with other forms of chemotherapy to treat colon cancer, melanoma, and head and neck cancer. It has also been used for treating dermatologic disorders such as verrucae. However, its benefits remain controversial and serious side effects such as central nervous system toxicity are unexpected.Case Report: Multifocal leukoencephalopathy developed in a 26-year-old man after levamisole treatment for verrucae. He recovered completely after discontinuation of the offending drug and treatment with steroid and plasmapheresis.Conclusion: Clinicians should be aware of this neurotoxicity in order to provide early diagnosis and treatment and thereby improve outcome.
延伸閱讀
- Tarafdar, S., Slee, M., Ameer, F., & Doogue, M. (2011). A Case of Valproate Induced Hyperammonemic Encephalopathy. Case Reports in Medicine, 2011(), 502-503-229. https://doi.org/10.1155/2011/969505
- Yang, S. Y., Chiu, T. F., & Chen, J. C. (2009). Levamisole-Induced Agranulocytosis Complicated with Deep Neck Infection. Journal of Emergency Medicine, Taiwan, 11(2), 71-75. https://www.airitilibrary.com/Article/Detail?DocID=15623386-200906-11-2-71-75-a
- 吳爵宏、盧璐（2008）。Levamisole-induced Multifocal Inflammatory Leukoencephalopathy: A Case Report。台灣復健醫學雜誌，36(4)，235-240。https://doi.org/10.6315/2008.36(4)05
- 李驊、文良彥（1989）。Treatment of Pseudophakic Bullous Keratopathy。中華民國眼科醫學會雜誌，28(2)，509-514。https://doi.org/10.30048/ACTASOS.198905.0094
- Lin, C. Y., Hsin, Y. L., & Tsao, W. L. (2009). Reversible Leukoencephalopathy Due to Cobalamin Deficiency after Subtotal Thyroidectomy for Graves' Thyrotoxicosis. 慈濟醫學雜誌, 21(1), 85-88. https://www.airitilibrary.com/Article/Detail?DocID=10163190-200903-21-1-85-88-a