糖尿病周邊神經病變患者的運動能力及平衡表現

Exercise Capability and Balance Performance in Patients with Diabetic Neuropathy

高宓憶(Mi-Yi Kao) ； 莊立民(Lee-Ming Chuang) ； 胡名霞(Ming-Hsia Hu) ； 謝松蒼(Sung-Tsang Hsieh) ； 吳英黛(Ying-Tai Wu)

《台灣醫學》 8卷3期 (2004/05) Pp. 323-331

https://doi.org/10.6320/FJM.2004.8(3).04

摘要

Peripheral neuropathy is a major complication of diabetic mellitus resulting in significant impairments. The purpose of this study was to compare exercise capability and balance performance in patients with different diabetic neuropathy severity measured by Modified Neuropathy Symptom Scores (NSS). Twenty-two patients were studied and were grouped into 1 (NSS≤2) or 2 (NSS≥ 3). All subjects then underwent a maximal exercise test and maximal oxygen consumption (VO2max) was obtained. Stroke volume at rest and during exercise as well as muscle strength and endurance of the left quadriceps were measured. Balance performance was evaluated with sensory organization test (SOT), unipedal stance time, and timed up and go test. Nonparametric Mann-Whitney U test was used to compare variables between groups. Correlations between different variables were analyzed by Spearman’s rank correlation coefficients. Group 1 had significantly lower values in VO2max (13.7±2.9 ml/min/kg versus 17.8 ±3.2 ml/min/kg), muscle strength (1.3±0.3N-m/kg versus 1.8±0.5 N-m/kg), unipedal stance time (17.1±15.5sec versus 37.1±12.8 sec), and SOT condition 6 (36.6±25.2% versus 61.9±8.4%) than that of group 2. Muscle strength significantly correlated with VO2max (r=0.74), unipedal stance time (r=0.55), and average balance score (r=0.47). the average balance score significantly correlated with all the variables, except for SOT condition 2, unipedal stance time, timed up ad go test, and muscle endurance. Our results showed that the severity of peripheral neuropathy symptoms did affect the exercise capacity and balance performance in patients with diabetic mellitus and the potential mechanism might due to different muscle strength among them. We suggest that muscle strengthening should be an integrated part of interventions for patients with diabetic neuropathy.

關鍵字

糖尿病 ； 周邊神經病變 ； 神經病變症狀分數 ； 運動能力 ； 平衡能力

並列摘要

Peripheral neuropathy is a major complication of diabetic mellitus resulting in significant impairments. The purpose of this study was to compare exercise capability and balance performance in patients with different diabetic neuropathy severity measured by Modified Neuropathy Symptom Scores (NSS). Twenty-two patients were studied and were grouped into 1 (NSS≤2) or 2 (NSS≥ 3). All subjects then underwent a maximal exercise test and maximal oxygen consumption (VO2max) was obtained. Stroke volume at rest and during exercise as well as muscle strength and endurance of the left quadriceps were measured. Balance performance was evaluated with sensory organization test (SOT), unipedal stance time, and timed up and go test. Nonparametric Mann-Whitney U test was used to compare variables between groups. Correlations between different variables were analyzed by Spearman’s rank correlation coefficients. Group 1 had significantly lower values in VO2max (13.7±2.9 ml/min/kg versus 17.8 ±3.2 ml/min/kg), muscle strength (1.3±0.3N-m/kg versus 1.8±0.5 N-m/kg), unipedal stance time (17.1±15.5sec versus 37.1±12.8 sec), and SOT condition 6 (36.6±25.2% versus 61.9±8.4%) than that of group 2. Muscle strength significantly correlated with VO2max (r=0.74), unipedal stance time (r=0.55), and average balance score (r=0.47). the average balance score significantly correlated with all the variables, except for SOT condition 2, unipedal stance time, timed up ad go test, and muscle endurance. Our results showed that the severity of peripheral neuropathy symptoms did affect the exercise capacity and balance performance in patients with diabetic mellitus and the potential mechanism might due to different muscle strength among them. We suggest that muscle strengthening should be an integrated part of interventions for patients with diabetic neuropathy.

並列關鍵字

diabetes mellitus ； peripheral neuropathy ； exercise capability ； balance performance