The purpose of this study was to investigate the symptom distress and its related factors in autoimmune disease patients while receiving the methylprednisolone pulse therapy. Subjects were recruited from autoimmune disease patients who were treated with methylprednisolone pulse therapy. A structured questionnaire of symptom distress was used as an instrument to collect data. The questionnaire was validated by using expert validity and reliability test with Cronbach's α .91. The results revealed that there were significant differences in symptom distress at three time points, before therapy, 1 week and 2 week post-therapies (p<.001). In addition, the factors of sex, complications, body weight, treatment dose, diagnosis and length of hospital stay were significantly correlated with symptom distress (p<.01). Complications, body weight change and previous disease history were three most important variables to predict symptom distress for patients with methylprednisolone pulse therapy. These variables explained 45.3% of the variation of total symptom distress. The study results indicated that nurses had to concern about the priority of the care and contents of patients' symptom distress for satisfying patients' demand to achieve the goal of self-care and maintain optimal physical condition in the self-care instruction.
The purpose of this study was to investigate the symptom distress and its related factors in autoimmune disease patients while receiving the methylprednisolone pulse therapy. Subjects were recruited from autoimmune disease patients who were treated with methylprednisolone pulse therapy. A structured questionnaire of symptom distress was used as an instrument to collect data. The questionnaire was validated by using expert validity and reliability test with Cronbach's α .91. The results revealed that there were significant differences in symptom distress at three time points, before therapy, 1 week and 2 week post-therapies (p<.001). In addition, the factors of sex, complications, body weight, treatment dose, diagnosis and length of hospital stay were significantly correlated with symptom distress (p<.01). Complications, body weight change and previous disease history were three most important variables to predict symptom distress for patients with methylprednisolone pulse therapy. These variables explained 45.3% of the variation of total symptom distress. The study results indicated that nurses had to concern about the priority of the care and contents of patients' symptom distress for satisfying patients' demand to achieve the goal of self-care and maintain optimal physical condition in the self-care instruction.
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