- 期刊
- OpenAccess
Performance of Stereotactic Vacuum-assisted Biopsy on Breast Microcalcifications: Comparison of 7-gauge and 10-gauge Biopsy Needles
摘要
PURPOSE. Stereotactic vacuum-assisted breast biopsy (VABB) is an important technique to diagnose isolated breast microcalcifications. Larger specimens obtained facilitate the early cancer assessment. MATERIALS AND METHODS. We retrospectively reviewed the stereotactic VABB on breast microcalcification in our hospital and compared the diagnostic performances of using 7-gauge (7-G) and 10-gauge (10-G) VABB needles. RESULTS. A total of 628 patients (187 biopsied by 7-G needle and 441 by 10-G needle) were included for analyses, showing 18.47% prevalence for breast cancers. Regarding the results of 153 cases with surgical pathology and 475 with clinical follow-up for at least 2-year, the overall cancer sensitivity was counted to 92.24%, specificity to 98.24% and accuracy to 98.63%. The accuracies, sensitivities and complete retrieval of microcalcifications by 7-G and 10-G needles were 100% to 97.27% (p = 0.022), 100% to 86.36% (p = 0.067) and 37.97% to 24.04% (p ＜ 0.001), respectively. Of the biopsies (42 by 7-G and 111 by 10-G) with subsequent surgical proof, the false negative rates were 0% and 9.01%, respectively; the upgrade rates of atypia lesions were 0% and 26.47%; and the upgrade rates of ductal carcinoma in situ were 15.38% and 9.10%. The cancer sensitivity of specimens with calcifications was higher for 7-G than 10-G VABB, but no significant difference for the specimens without calcifications. CONCLUSION. Both 7-G or 10-G VABB could diagnosed suspicious microcalcifications of the breasts; however, 7-G needle had higher cancer sensitivity, accuracy, upgrade rate of atypia lesions and complete retrieval of microcalcifications.
延伸閱讀
- Ibarra, J. A. (2012). The Value of Combined Large Format Histopathology Technique to Assess the Surgically Removed Breast Tissue following Neoadjuvant Chemotherapy: A Single Institution Study of 40 Cases. International Journal of Breast Cancer, 2012(), 107-111. https://doi.org/10.1155/2012/361707
- Yu, K. L., Yang, H. C., Ko, J. C., Ho, C. C., & Shih, J. Y. (2021). Feasibility of Re-biopsy by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) in Patients with Previously Treated Lung Cancer. 胸腔醫學, 36(2), 71-80. https://www.airitilibrary.com/Article/Detail?DocID=10239855-202106-202107260015-202107260015-71-80
- Langen, H. J., Koehler, S., Bielmeier, J., Jocher, R., Kranzfelder, D., Jagusch, N., Treutlein, G., Wetzler, T., J.Muller, & Ott, G. (2012). Microradiography of Microcalcifications in Breast Specimen: A New Histological Correlation Procedure and the Effect of Improved Resolution on Diagnostic Validity. Radiology Research and Practice, 2012(), 158-170. https://doi.org/10.1155/2012/526293
- Hung, S. H., Lee, N. H., Tseng, C. M., Lin, C. H., Chen, R. C., & Chou, J. M. (2008). Diagnostic Accuracy of Ultrasound-guided Core Needle Biopsy for Breast Cancer. 北市醫學雜誌, 5(1), 15-22. https://doi.org/10.6200/TCMJ.2008.5.1.02
- Ito, H., Inoue, H., Ryozawa, S., Ikeda, H., Odaka, N., Eleftheriadis, N., Maselli, R., Sando, N., Kimura, S., & Kudo, S. E. (2012). Fine-Needle Aspiration Biopsy and Endoscopic Ultrasound for Pretreatment Pathological Diagnosis of Gastric Gastrointestinal Stromal Tumors. Gastroenterology Research and Practice, 2012(), 36-41-004. https://doi.org/10.1155/2012/139083