Title

氨基甲酸化合物抑制青黴素酶與籠狀化合物抑制乙和丁醯膽鹼酯酵素之分子對接研究

Translated Titles

Molecular Dockings of Carbamates into Penicillinase and Cage Compounds into Acetyl-and Butyryl-cholinesterases

DOI

10.6845/NCHU.2012.01291

Authors

翁姿婷

Key Words

分子對接 ; 青黴素酶乙和丁醯膽鹼酯酵素 ; Molecular Dockings ; Penicillinase ; Acetyl-and Butyryl-cholinesterases

PublicationName

中興大學化學系所學位論文

Volume or Term/Year and Month of Publication

2012年

Academic Degree Category

碩士

Advisor

林家立

Content Language

繁體中文

Chinese Abstract

摘要 將氨基甲酸(carbamates) 分子對接於青黴素酶(Penicillinase)的X-射線結晶,預測結果與文獻上動力學實驗數據相左。將籠狀化合物分子對接於老鼠的乙醯膽鹼酯酵素和人類的丁醯膽鹼酯酵素的X-射線結晶,預測結果與文獻上動力學實驗數據相佐證。

English Abstract

Abstract Molecular docking of carbamates into the X-ray crystal structure of penicillinase confirmed the experimental results from the literature. Molecular dockings of cage compounds into the X-ray crystal structures of mouse acetylcholinesterase and human butyrylcholinesterase confirmed those experimental kinetic data from the literature.

Topic Category 基礎與應用科學 > 化學
理學院 > 化學系所
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Times Cited
  1. 呂仁傑(2014)。硫代胺基甲酸類與β-內醯胺酶和凝血酶分子對接研究。中興大學化學系所學位論文。2014。1-87。 
  2. 連偉翔(2013)。聯苯磺酸纇與老鼠和人類乙醯膽鹼酯酵素之分子對接。中興大學化學系所學位論文。2013。1-88。