Translated Titles

Impact of Continuous Subcutaneous Insulin Infusion Therapy on Glucose Control and Quality of Life for Patients with Diabetes--An Example from Taiwan





Key Words

胰島素幫浦 ; 血糖控制 ; 糖化血色素 ; 低血糖 ; 生活品質 ; Continuous subcutaneous insulin infusion (CSII) ; Insulin pump therapy ; Hypoglycaemia ; Quality of life



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Content Language


Chinese Abstract

本研究之主要目的在針對臺灣地區使用胰島素幫浦方式治療之糖尿病患,評估其血糖控制與生活品質成效。研究方法以結構性問卷的方式,確定患者的特點,治療效果及治療滿意度. 研究結果問卷回收率41.92%,89.8%為第一型糖尿病患者。問卷調查結果反應胰島素幫浦的使用者獲得了良好的血糖控制,平均糖化血色素的水平為7.1 +/-1.1%.且有滿意的生活品質,值得供糖尿病患者做為選擇治療的方式.

English Abstract

The purpose of this study were to understand the characteristics and attitude of patients treated with continuous subcutaneous insulin infusion (CSII), and the impact on glycaemic control in CSII patients of Taiwan in routine daily life and quality of life. A structured questionnaire was distributed to 167 CSII patients from 2001 years until now to determine patient characteristics, therapy characteristics, medical results, complications and treatment satisfaction. A 41.92% response rate was achieved, 89.8% from patients with Type 1 diabetes. The responses indicated that CSII users achieved good glycaemic control with a mean HbA1c level of 7.1±1.1%. These data suggest patients using CSII therapy achieve good metabolic control, are highly satisfied, and experience an acceptably small number of complications.

Topic Category 醫藥衛生 > 醫院管理與醫事行政
公共衛生學院 > 醫務管理學研究所
社會科學 > 管理學
  1. 行政院衛生署98年度死因統計
  2. 傅振宗和楊文琴(2003)。糖尿病患的護心運動。基層醫學,18(5) ,124-127。
  3. 鍾遠芳、林宏達(2000)。糖尿病衛教對病患知識、態度、行為及代謝指標的影響。中華民國內分泌暨糖尿病學會會訊,13(3),1-17。
  4. Aljabri K, Kozak SE, Thompson DM. (2004) ;Addition of pioglitazone or bedtime insulin to maximal doses of sulfonylurea and metformin in type 2 diabetes patients with poor glucose control: a prospective, randomized trial. American Journal of Medicine;116(4):230-5Aljabri K.Horton ES, Clinkingbeard C, Gatlin M, et al. (2000 );Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes. Diabetes Care;23(1):1660-5
  5. Andrew J. Ahmann, MD, Diabetes Physician Recognition Program, DPRP(2007);
  6. Ann Intern Med. (1995), DCCT Research Group; 122:561-568
  7. Education for adults with type 2 diabetes : a meta-analysis on the effect on glycemic control. Diabetes Care 25 :1159-1171
  8. Goudswaard AN, Furlong NJ, Rutten GE, et al. (2005) ;Insulin monotherapy versus combinations of insulin with oral hypoglycaemic agents in patients with type 2 diabetes mellitus. Cochrane Database of Systematic Reviews;20
  9. Greeshma Shetty, Howard Wolpert,(2010); Insulin Pump Use in Adult with Type 1 Diabetes-Practical Issue. Diabetes Technology & Therapeutics. Vol. 12, Suppl. 1, 2010
  10. Hammond P, Liebl A, Grunder S. (2007); International survey of insulin pump users : Impact of continuous subcutaneous insulin infusion therapy on glucose control and quality of life. Prim Care Diabetes. (2007) Sep;1(3):143-146.
  11. Helen J.,Lynn E.,T. Michael Vallis, Laurie R., et al. ( 2003); Changes in Diabetes Self-Care Behaviors Make a Difference in Glycemic Control : The Diabetes Stages of Change (DiSC) study. Diabetes Care Mar. 2003 vol. 26 no. 3, 732-737
  12. Kidney Int. (1995), DCCT Research Group; 47:1703-1720
  13. Lin T& Chou P, Lai MS& Tsai ST, Tai TY. (2001) Nov. ; Diabetes Research & Clinical Practice. 54 Suppl 1:S43-6
  14. Martha M., Tammy L., Belinda P., Linda B., et al (2008); National Standards for Diabetes Self-Management Education. Diabetes Care January 2008; vol. 31 no. Supplement 1 S97-S104.
  15. Meaghan E. St. Charles, Hamid Sadri, MSc, Michael E. et al.( 2009); Health economic comparison between continuous subcutaneous insulin infusion and multiple daily injections of insulin for the treatment of adult type 1 diabetes in Canada. Clinical Therapeutics. Vol. 31, Issue 3, Mar. 2009, 657-667
  16. Mitra M., Fatourechi, Yogish C., Kudva, M. Hassan Murad, et al.(2009); Hypoglycemia with Intensive Insulin Therapy : A Systematic Review and Meta-Analyses of Randomized Trials of Continuous Subcutaneous Insulin Infusion Versus Multiple Daily Injections. J Clin Endocrinol Metab, March 2009, 94(3):729-740
  17. Nathan DM, Buse JB, Davidson MB, et al. (2009);Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy. Diabetologia;52:17-30Wei JN& Sung FC&Lin CC& Lin RS&Chiang CC& Chuang LM. (2003) Sep 10 ; JAMA. 290(10):1345-50
  18. N Engl J Med. (1993 )Sep 30;The diabetes control and complications trial. Implications for policy and practice. 329(14):977-86 329 (14): 977
  19. Norris SL, Lau J., Smith SJ, Schmid CH, Engelgau MM(2002) : Self-management
  20. Ophthalmology. (1995), DCCT Research Group; 102:647-661
  21. Pickup JC, Sutton AJ. (2008); Severe hypoglycaemia and glycaemic control in Type 1 diabetes : meta-analysis of multiple daily insulin injections compared with continuous subcutaneous insulin infusion. Diabet Med 2008;25:765-774
  22. Roter D, Kinmonth A-L.(2002) What is the evidence that increasing participation of individuals in self-management improves the processes and outcomes of care?
  23. Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, Hadden D,
  24. The Diabetes Educator (2003);American Association of Diabetes Educators. Position Statement: Standards for Outcomes Measurement of Diabetes SelfManagement Education. The Diabetes Educator 2003; 29:804-16.
  25. Turner RC, Holman RR (2000); Association of glycaemia with macrovascula and microvascular complications of Type2 diabetes: prospective observational study. British Medical Journal 2000;321:405-412
  26. UK Prospective Diabetes Study Group (1998); Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. (UKPDS 33) Lancet. 1998;352:837-853
  27. Weng J, Li Y, Xu W, et al.(2008); Effect of intensive insulin therapy on β- cell function and glycaemic control in patients with newly diagnosed type 2 diabetes. Lancet 2008; 371:1753-1760
  28. Williams R, Kinmonth A, Wareham N, Herman W, eds. (2002) The Evidence Base for Diabetes Care. John Wiley and Sons, 2002.
  29. Yves R., Julia M., Anne R., Christine C., et al .(2010); Efficacy of Continuous Subcutaneous Insulin Infusion in Type 2 Diabetes Mellitus : A Survey on a Cohort of 102 Patients with Prolonged Follow-Up. Diabetes Technology & Therapeutics. Dec. 2010, 12(12):931-936
  30. 參考文獻
  31. 中文部份
  32. 游能俊 (2006年11月) , 2006年糖尿病健康促進機構品質狀況調查報告
  33. 邱玉珍 (2009年12月) , 時報周刊 7大指標 掌控血糖,2009/12/25∼12/31,69-71
  34. 李佩儒、翁慧卿、徐慧君、劉姝妮、李集美、方淑音等人(2004)。「全民健保糖尿病醫療服務改善方案」?o某區域教學醫院執行一年之成果報告。台灣醫界,47(4),44-47。
  35. 中華民國糖尿病學會(2010) 。糖尿病臨床照護指引,2010,11(3) ,54-59
  36. 英文部份
  37. Guidelines and Performance Measures for Diabetes. Volume 13: S41-S46 April 2007 Number 2 Suppl
  38. Gulias-Herrero A, Aquilar-Salinas CA, Gomez-Perez FJ, Rull JA. (2003) Oct-Dec; The combination metformin/glyburide exerts its hypoglycemic effect mainly by increasing insulin secretion : a controlled, randomized, double-blind, crossover study. Diabetes Nutr Metab. ;16(5-6):268-76
  39. Howard Wolpert, (2002); Smart Pumping, ADA 2002,Nov. 5
  40. Irl Hirsch. (2005); The reduced risk may result from less glucose variability seen with pumps and MDI. Amer J Med,118(5A) : 21S-26S
  41. Li HY& Wei JN& Sung FC& Chuang LM. (2006) ; Diabetes Care ; 29(10): 2326; Diabetes Care ;(2011)January , vol. 34 no. Supplement 1 S62-S69
  42. Mark Allen ( 2007 )Sep; British Journal of Nursing. 16(16):1002-7, 13-27 ChenX& Tang L&Chen H et al. ( 2003). ; Chinese Health Economic Magazine ; 22(12): 21-3.
  43. Mathijs Vogelzang&Iwan CC van der Horst&Maarten WN Nijsten(2004 ) Jun. ;Critical Care (London, England). 8(3):R122-7
  44. T. Battelino, B.W. Bode. (2010); Continous glucose monitoring in 2010. Internaional Journal of Clinical Practice. Vol. 65, Issue Suppl. S170,10-15, Feb. 2011
Times Cited
  1. 林宥安(2014)。以健保資料庫與癌症登記檔建構糖尿病確診後罹患為肝癌之預測模型。臺北醫學大學醫學資訊研究所學位論文。2014。1-55。