Vitamin D Status of Maori and Non-Maori Octogenarians from Life and Living in New Zealand: a Cohort Study (LiLACS NZ)

Catherine J Bacon ； Ngaire Kerse ； Karen J Hayman ； Simon A Moyes ； Ruth O The ； Mere Kepa ； Avinesh Pillai MSc ； Lorna Dyall

《Asia Pacific Journal of Clinical Nutrition》 預刊文章 Pp. 220-244

https://doi.org/10.6133/apjcn.092015.42

並列摘要

Objective: This study assessed vitamin D status and its determinants in a cohort of octogenarians living within New Zealand's Bay of Plenty and Lakes Districts. Methods: Serum 25-hydroxyvitamin D [25(OH)D] concentration was measured in 209 Māori (aged 80-90 years) and 357 non-Māori (85 years), along with demographic, lifestyle, supplement use and other health data. Results: Mean [95% CI] 25(OH)D concentration was 69 [67 to 72] nmol/L, with 15% ＞100 nmol/L and 6 individuals ＞150 nmol/L. Concentrations in Māori (59 [55 to 62] 4 nmol/L) were lower than in non-Māori (75 [72 to 78] nmol/L; p＜0.001), a difference maintained when adjusted for day-of-year measured. Vitamin D supplementation was reported by 98 participants (18%): including a greater proportion of women (24%) than men (11%; p＜0.001) and of non-Māori (24%) than Māori (7%; p＜0.001). Of those taking vitamin D, 49% took high oral doses (≥25 μg/day or equivalent) and five individuals took ＞50 μg/day. Vitamin D supplement use strongly and independently predicted seasonally-adjusted 25(OH)D concentration and was associated with 28 nmol/L higher levels than non-use. Other predictors included Māori ethnicity (10 nmol/L lower concentration than for non-Māori), and female gender (11 nmol/L lower). Discussion and Conclusions: Vitamin D status in New Zealand octogenarians appears higher than previously reported, particularly in non-Māori compared to Māori. Prescribed and non-prescribed oral vitamin D supplementation is prevalent in this group and a strong indicator of vitamin D status.

並列關鍵字

calciferol ； seasonal variation ； ethnic groups ； aged ； 80 and over ； elderly