Long-term Survival after Combined Heart and Kidney Transplantation: Report of a Case

心腎合併移植後長期存活：病例報告

張兼華(Chien-Hwa Chang) ； 周迺寬(Nai-Kuan Chou) ； 許榮彬(Ron-Bin Hsu) ； 朱樹勳(Shu-Hsun Chu) ； 李伯皇(Poh-Huang Lee) ； 王水深(Shoei-Shen Wang)

《Formosan Journal of Surgery》 40卷1期 (2007/02) Pp. 25-29

https://doi.org/10.29833/FJS.200702.0004

摘要

心腎合併移植已經是一個被接受的治療選擇，與單獨心臟或腎臟移植相比，擁有較低的器官排斥率。我們在此報告一位病患於1995年在某醫學中心接受由單一捐贈者捐出心臟與腎臟之心腎合併移植手術。他是台灣第一位接受心腎合併移植手術的患者。在十年的追蹤期間，只有一次心臟排斥，沒有出現腎臟排斥的情形。心臟與腎臟功能目前依舊良好。我們回顧了關於移植免疫機轉與移植後併發症之文獻。總結來說，對心臟與腎臟末期衰竭的病患，心腎合併移植是一個可行的方式。在十年的追蹤期間，這位病患只有一次排斥的紀錄。他在移植後長期存活並且心臟及腎臟運作正常。

並列摘要

Combined heart and kidney transplantation (CHRT) has been an acceptable therapeutic option with a lower allograft rejection rate than isolated heart or kidney transplantation. Herein we present a patient who received CHRT using a single donor at a medical center in 1995. This is the first case of CHRT in Taiwan. After ten years follow up, no renal rejection but one episode of cardiac rejection has been noted. Cardiac function and renal function have remained normal. We reviewed the literature about immunology and post-transplantation complications of CHRT. In conclusion, CHRT is a feasible procedure for patients with end-stage cardiac and renal failure. This patient, with only one episode of rejection has attained long-term survival with fair cardiac and renal function.

並列關鍵字

combined heart and kidney transplantation ； post-transplantation ； rejection ； long-term survival