食用核桃對醫院員工心血管代謝危險因子與肥胖之影響

Effect of Walnut Consumption in Cardio-metabolic Risk and Adiposity Among Hospital Employees

吳得束(Te-Shu Wu) ； 丁良文(Liang-Wen Ding) ； 吳佩瑜(Pei-Yu Wu) ； 翁德志(Te-Chih Wong) ； 楊淑惠(Shwu-Huey Yang)

《臺灣營養學會雜誌》 42卷1期 (2018/03) Pp. 23-32

https://doi.org/10.6691/NSJ.201803_42(1).0003

摘要

核桃富含營養素及多元不飽和脂肪酸，尤其是-亞麻油酸（ALA），是以植物為主的ω-3必須脂肪酸，具抗發炎及抗動脈粥狀硬化的作用。本研究採雙臂、隨機控制試驗，在核桃飲食介入8週後評估對心血管危險因子，如血脂、血糖與肥胖指標之影響。受試者資料收集包含身高、體重、肥胖指標的測量（頸圍、腰圍、臀圍及大腿圍）、血脂及血壓，共有33位（23位核桃組及10位非核桃組）完成試驗。比較非核桃組受試者於試驗前後其腰圍、總膽固醇、低密度脂蛋白膽固醇、non HDL-C及血壓皆無顯著差異，相較於核桃組飲食介入前後各數值之變化，其腰圍（-3.1 cm, p=0.001）、總膽固醇（-12.4 mg/dL, p=0.003）、低密度脂蛋白膽固醇（-8.9 mg/dL, p=0.028）、non HDL-C（-10.7 mg/dL, p=0.009）及收縮壓（-4.8 mmHg, p=0.014）、舒張壓（-3.3 mmHg, p=0.044）皆達顯著差異。本研究結果顯示，具心血管疾病風險的個案每日食用56 g核桃持續8週可顯著降低腰圍、血脂及血壓，有助於改善心血管代謝危險。

關鍵字

心血管代謝危險 ； 核桃 ； non HDL-C ； 肥胖指標

並列摘要

Walnuts are rich in nutrients and polyunsaturated fatty acids-mainly, linoleic acid and alpha-linolenic acid, a plant-based essential ω-3 fatty acid with anti-inflammatory and antiatherogenic effects. In this two-arm randomized control trial, we performed a nutrition intervention study to assess the effects of an 8-week walnut diet on the blood lipid profile, glycemic control, and adiposity. Data of a subject's height, body weight, adiposity index measurements (neck, waist, hip, and thigh circumferences), plasma lipid profile, and blood pressure (BP) were collected. In total, 33 subjects (23 in the walnut group and 10 in the non-walnut group) completed the trial. There were no statistical differences in waist circumference, total cholesterol, low-density lipoprotein cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C), or BP in the non-walnut group before and after the intervention. However, the waist circumference (-3.1 cm, p =0.001), total cholesterol (-12.4 mg/dL, p = 0.003), LDL-C (-8.9 mg/dL, p =0.028), non-HDL-C (-10.7 mg/dL, p =0.009), systolic BP (-4.8 mmHg, p =0.014), and diastolic BP (-3.3 mmHg, p =0.044) had significantly decreased after this 8-week intervention in the walnut group. This study showed that daily consumption of 56 g of walnuts for 8 weeks significantly reduced the waist circumference, plasma total-, LDL- and non-HDL-cholesterol, and BP in subjects with preferable characteristics, thus improving their cardiometabolic risk.

並列關鍵字

cardiometabolic risk ； walnuts ； non-HDL-C ； adiposity index