Seminal vesicle metastasis of a primary small cell lung cancer (SCLC) is rare. We present the case of a 59-year-old male who was diagnosed with SCLC of the left upper lung in January 2011 and was treated with chemotherapy and radiotherapy. He was later admitted for complaints of anal pain and dysuria during his regular follow-up. Abdominal computed tomography scan revealed an 8×5.5 cm mass in the left seminal vesicle. Histopathology after trans-rectal ultrasound-guided biopsy confirmed the diagnosis of SCLC. The patient then underwent concurrent chemo-radiotherapy (CCRT). His post-CCRT follow-up at 3 months showed complete response and no recurrence. The management of patients with lung cancer and dysuria should consist of a multi-disciplinary approach, and urologic organ metastasis should be included among the differential diagnoses.
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