- 期刊
Vitiligo Universalis Associated with Evans Syndrome and Antiphospholipid Syndrome: A Case Report and Review of the Literature
全身性白斑合併Evans徵候群及antiphospholipid徵候群：病例報告與文獻回顧
摘要
白斑的致病機轉被推斷和自體免疫所導致的黑色素細胞破壞有關。自體免疫溶血性貧血合併出現血小板低下症，稱之為Evans徵候群；而antiphospholipid徵候群，則是在出現antiphospholipid抗體情況下，導致動脈或靜脈血栓、反覆流產或血小板低下情形。我們報告一例罕見的全身性白斑合併Evans徵候群及antiphospholipid徵候群之病例，此關聯性在以前從未被報告過。此病例與多個免疫疾病的相關性也支持其免疫學方面的致病機轉。
關鍵字
無資料並列摘要
The pathogenesis of vitiligo has been proposed as a destruction of melanocytes by autoimmune processes. Evans syndrome is the combination of autoimmune hemolytic anemia and immune-mediated thrombocytopenia. The antiphospholipid syndrome is characterized by arterial/venous thrombosis, recurrent pregnancy loss, or thrombocytopenia in the presence of antiphospholipid antibodies. We present a case of vitiligo universalis associated with Evans syndrome and antiphospholipid syndrome, the association of which has not been reported before. The association of multiple autoimmune diseases in our case also support the theory that vitiligo may result from immune dysregulation.
延伸閱讀
- Chang, Y. C., Wu, J. M., Lin, S. J., & Wu, M. H. (1995). Ellis-van Creveld症候群合併單心房及Ebstein's異常：一病例報告. Acta Paediatrica Sinica, 36(1), 50-52. https://doi.org/10.7097/APS.199502.0050
- 胡嘉麟、陳立民、賴啟賢（2001）。紅斑性狼瘡合併抗磷脂徵候群：一病例報告與文獻回顧。Journal of Medical Sciences，21(1)，53-57。https://www.airitilibrary.com/Article/Detail?DocID=10114564-200102-201305200002-201305200002-53-57
- Lin, C. H., Lai, C. H., Lin, W. C., Wu, K. H., Chen, A. C., Lin, H. C., & Chang, J. S. (2006). 以猛暴性肺出血為最初表現之全身性紅斑性狼瘡：－病例報告與文獻回顧. 中華民國兒童胸腔醫學會雜誌, 5(2), 81-88. https://doi.org/10.6322/JPRD.200607_5(2).0005
- 陳建維、楊中美、楊長豪、陳慕師（1994）。多發閃現性白點症候群－病例報告與文獻回顧。中華民國眼科醫學會雜誌，33(1)，112-120。https://doi.org/10.30048/ACTASOS.199403.0017
- 曾柏蒼、陳萬宜（2021）。後天免疫缺乏症候群相關卡波西氏肉瘤－病例報告及文獻回顧。臺灣口腔顎面外科學會雜誌，32(4)，322-333。https://www.airitilibrary.com/Article/Detail?DocID=a0000494-202112-202111190007-202111190007-322-333