The educational policy of regular class placement and ideal practice for inclusive education are becoming one of the challenges for teachers in Taiwan today. These challenges include: teaching in a mixed-level classroom and being limited or unable to take into account or meet the diverse learning needs of every student. Based on the viewpoint of "adaptive instruction", this paper introduced the ways to implement differentiated teaching from the following six dimensions. 1. Process of differentiated curriculum design, 2. How to implement differentiated instruction for gifted students, 3. Principles of modifying teaching for special needs, 4. What are the ways to implement differentiated instruction in regular classroom? 5. How can easily start differentiated instruction? and 6. Some useful differentiated teaching strategies for gifted and talented students.