接受類固醇脈衝治療自體免疫疾病病人之症狀困擾及相關因素

Symptom Distress and Related Factors in Autoimmune Disease Patients Receiving Methylprednisolone Pulse Therapy

白玉珠(Yu-Chu Pai) ； 洪曉佩(Shiao-Pei Hung) ； 黃鈴雅(Ling-Ya Huang) ； 朱紋瑩(Wurn-Yirng Ju) ； 黃朱貝(Chu-Bei Huang)

《新臺北護理期刊》 12卷1期 (2010/04) Pp. 21-31

https://doi.org/10.6540/NTJN.2010.1.003

摘要

The purpose of this study was to investigate the symptom distress and its related factors in autoimmune disease patients while receiving the methylprednisolone pulse therapy. Subjects were recruited from autoimmune disease patients who were treated with methylprednisolone pulse therapy. A structured questionnaire of symptom distress was used as an instrument to collect data. The questionnaire was validated by using expert validity and reliability test with Cronbach's α .91. The results revealed that there were significant differences in symptom distress at three time points, before therapy, 1 week and 2 week post-therapies (p＜.001). In addition, the factors of sex, complications, body weight, treatment dose, diagnosis and length of hospital stay were significantly correlated with symptom distress (p＜.01). Complications, body weight change and previous disease history were three most important variables to predict symptom distress for patients with methylprednisolone pulse therapy. These variables explained 45.3% of the variation of total symptom distress. The study results indicated that nurses had to concern about the priority of the care and contents of patients' symptom distress for satisfying patients' demand to achieve the goal of self-care and maintain optimal physical condition in the self-care instruction.

關鍵字

脈衝治療 ； 自體免疫疾病 ； 症狀困擾

並列摘要

The purpose of this study was to investigate the symptom distress and its related factors in autoimmune disease patients while receiving the methylprednisolone pulse therapy. Subjects were recruited from autoimmune disease patients who were treated with methylprednisolone pulse therapy. A structured questionnaire of symptom distress was used as an instrument to collect data. The questionnaire was validated by using expert validity and reliability test with Cronbach's α .91. The results revealed that there were significant differences in symptom distress at three time points, before therapy, 1 week and 2 week post-therapies (p＜.001). In addition, the factors of sex, complications, body weight, treatment dose, diagnosis and length of hospital stay were significantly correlated with symptom distress (p＜.01). Complications, body weight change and previous disease history were three most important variables to predict symptom distress for patients with methylprednisolone pulse therapy. These variables explained 45.3% of the variation of total symptom distress. The study results indicated that nurses had to concern about the priority of the care and contents of patients' symptom distress for satisfying patients' demand to achieve the goal of self-care and maintain optimal physical condition in the self-care instruction.

並列關鍵字

Autoimmune disease ； Pulse therapy ； Symptom distress