Primary Clinical Practice is the first and necessary practicum required for nursing students. Many of them are under great pressure for environmental change and therefore their daily routine is severe affected. To study these nursing students' practice stress and sleeping quality, we took a weekly based running survey on 211 nursing students during the primary clinical practice period. The survey focuses on how much pressure they were facing on the job and how they managed it. We did a cross-lagged panel analysis on the two issues. We found out that working pressure is highly related with sleeping quality, and both practice stress and sleeping quality are gradually improved with time progressing.