亞洲勃起功能障礙流行率統合分析

Erectile Dysfunction and Life Style in Old Age

吳敏倫(Man-Lun Ng) ； 鄭英偉(Jackie Ying-Wai Cheng)

《性學研究》 1卷2期 (2010/07) Pp. 35-60

摘要

我們通過Medline、Pubmed、PsycInfo和閱覽參考文獻目錄，搜索已發表了的有關亞洲人口勃起功能障礙(erectile dysfunction, ED)流行率的研究，取得並總結每個亞洲地區ED流行率的數據，用於計算匯集流行率，使用固定和隨機效應模型作合併流行率估計。由於顯著的異質性存在於某些年齡組，隨機效應模型爲估計的首選。我們集合了21篇人口研究進行鑑定，6個研究有資格進入匯集，提供共8,653人進行分析。ED的患病率隨著年齡增加。由隨機效應模型匯集估計的特定年齡ED流行率，在20-29、30-39、40-49、50-59及60-69歲年齡組中分別爲15.1%(12.2-18.1)、29.6%(19.7-39.6)、40.6%(23.6-57.7)、54.3%(36.0-72.6)和70.0%(62.3-77.7)。20-29歲組和60-69歲組結果的同質性顯示在亞洲不同地區，這些年齡組有同樣低和高的ED流行率。總流行率在個別研究中，範圍由2%到81.8%。本文也總結了各亞洲地區有關ED流行率的研究及相關資料。

關鍵字

勃起功能障礙 ； 性功能障礙 ； 流行病學 ； 亞洲 ； 統合分析

並列摘要

This is a cross-section study of male erectile dysfunction in old age. From a primary care treatment center in Hong Kong, 160 sexually active males (who had sexual intercourse in the previous 6 months) aged above 65 were compared with, a matched group of males aged 50-65. Living standard was measured by the availability of domestic helpers and housing types. The overall response rate was 66.9%. Participants were in general wealthier than the non-participants. Those who employed domestic helpers had erectile index (IIEF-15) significantly higher (p=0.02), independent of the type of housing. In statistical model A which included the salary and educational level, the monthly income and erectile function (EF), sexual satisfaction (IS), orgasm (OS) and sex desire (SD) areas showed significant non-parametric interaction. After statistical adjustment, only EF (p＜0.01) and IS (p=0.04) remained positively correlated with the monthly income. In multivariate analysis, orgasmic function negatively correlated with age (p＜0.01) and diabetes (p=0.04); sexual desire was negatively correlated with age (p＜0.01) and overall life satisfaction were not significantly correlated with any factors studied. In model B (which excluded monthly income), education level was definitely linked with EF (p=0.04), but this link disappeared after adjustment for multiple test effects. In the final multi-factorial model, only monthly income (p＜0.01) and age (p＜0.01) correlated with erectile function, not the level of education (p=0.47). This study shows that social factors can affect erectile function, and the effect can be extended to old age.

並列關鍵字

Sexual Dysfunction ； IIEF ； Old Age ； Life Style ； Chinese

參考文獻

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