In this study, the local mixed sample was prepared from the sediment of the Varus Creek bed, and the compressive strength test was carried out with different ratios, ages and water-cement ratios. As a major reference for assessing the nature sediment in this river to facilitate subsequent research or governance engineering projects. The comprehensive research observation data and test analysis results show that the growth rate of the compressive strength of this test sample with higher specific gravity and lower water-cement ratio is lower. The proportion of coarse aggregate is lower, and the higher growth rate of sample water-cement ratio is higher. Therefore, the cement ratio and water-cement ratio are important factors affecting the strength of local in-situ mixing.