- 期刊
- OpenAccess
Phytochemical Screening and Effect of Musa paradisiaca Stem Extrude on Rat Haematological Parameters
並列摘要
This study was carried out to investigate the phytochemical composition and effect of various concentrations of Musa paradisiaca stem extrude on haematological parameters in Albino Wistar rats. Twenty rats (62-121 g) were randomly assigned into 5 groups of 4 rats each. Group 1 the control group, were given ordinary water while the test groups 2, 3, 4 and 5 were given 25, 50, 75 and 100% of the aqueous extract, respectively without water for 28 days. Rats were sacrificed and blood samples were collected by cardiac puncture then used for the haematological studies. Phytochemical tests were carried out using standard laboratory techniques. The results of the study show the presence of tannins and glycosides in abundance in the stem extrude while saponins, flavonoids, alkaloids, polyphenols and reducing sugars were present in moderate amounts but phlobatannins was absent. There was a significant (p＞0.05) increase in rat RBC, PCV, Hb and WBC counts at concentrations of 75 and 100% when compared with the control and a significant (p＞0.05) decrease in MCH and MCHC. The levels of MCV were not significantly altered at all extract concentrations. It can therefore be concluded that Musa paradisiaca stem extrude has a haematopoietic and immunomodulatory effect consistent with its ethnomedicinal use.
延伸閱讀
- 林卉梅（2006）。Protective effects of the fruit of Ligustrum lucidum on acute butylated hydroxytoluene-induced oxidative stress in rats〔碩士論文，高雄醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0011-1406200605520500
- Akindele, A. J., Iyamu, E. A., Dutt, P., Satti, N. K., & Adeyemi, O. O. (2014). Ameliorative Effect of Hydroethanolic Leaf Extract of Byrsocarpus coccineus in Alcohol- and Sucrose-Induced Hypertension in Rats. Journal of Traditional and Complementary Medicine, 4(3), 177-188. https://doi.org/10.4103/2225-4110.129562
- Mahomoodally, M. F., & Dilmohamed, S. (2016). Antibacterial and antibiotic potentiating activity of Vangueria madagascariensis leaves and ripe fruit pericarp against human pathogenic clinical bacterial isolates. Journal of Traditional and Complementary Medicine, 6(4), 399-403. https://doi.org/10.1016/j.jtcme.2015.09.002
- Idonije, O. B., Asika, E. C., Okhiai, O. O., & Nweke, I. N. (2011). Phytochemical, Chromatographic and Antimicrobial Studies of the Ethanolic Extract of the Stem Bark of ＂Pentaclethra macrophylla＂ (African Oil Bean Tree). British Journal of Pharmacology and Toxicology, 2(6), 283-289. https://www.airitilibrary.com/Article/Detail?DocID=20442467-201112-201507070016-201507070016-283-289
- Mordi, J. C., & Akanji, M. A. (2012). Phytochemical Screening of the Dried Leaf Extract of Cnidoscolus aconitifolius and Associated Changes in Liver Enzymes Induced by its Administration in Wistar Rats. Current Research Journal of Biological Sciences, 4(2), 153-158. https://www.airitilibrary.com/Article/Detail?DocID=20410778-201203-201512280016-201512280016-153-158