- 期刊
The Urinary Excretion of 17 Ketosteroids and Δ^5 Pregnane-3α, 17α, 20α-Triol in Infancy, Childhood, Adolesence and Congenital Adrenal Hyperplasia
正常及先天性腎上腺增生兒童之17 ketosteroids和pregnantriol之尿排泄量
摘要
檢查81位自出生至15歲正常兒童尿中17 ketosteroid和pregnantriol排泄量的結果發現7歲前兒童之尿17 KS排泄量很少，從8歲至15歲間，其尿排泄量才逐漸增加。尿pregnantriol之排泄量雖然都很低，但隨年齡而逐漸增加。尿pregnantriol之排量男女間並無差別，但青春期男孩之尿17 KS排泄量略比女孩爲高，pregnantriol之排泄量與17 KS排泄量有正比相關。13位先天性腎上腺增生病童之尿17 KS和pregnantriol排泄量都顯然增加，且經治療後都顯著下降。
關鍵字
無資料並列摘要
Eighty one healthy infants and children without evidence of endocrine disorders were studied for urinary excretion of 17 ketosteroids (17 KS) and pregnantriol. The urinary 17 KS excretion was low and remained below 2.2 mg/day until the seventh year. From seven to fifteen years of age, it increased gradually. The urinary excretion of pregnantriol was low but increased with age. The excretion of 17 KS correlated well to that of pregnantriol. Patients with congenital adrenal hyperplasia excreted significantly larger amounts of 17 KS and pregnantriol for their age. The high urine steroid levels decreased significantly after treatment.