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嬰兒及兒童時期的僧帽瓣疾病

Mitral Valve Disease in Infancy and Childhood

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摘要


許多的文章都在探討成年人的僧帽瓣閉鎖不全症,而總其原因均爲風濕性的問題引起的原因居多。但是如果發生在嬰兒及兒童時期的話,除了風濕性的問題,首先應要攷慮有無先天性存在的可能性。本院導管室自民國65年至71年,共發現了9例是屬於先天性二尖瓣閉鎖不全症。這種疾病可分爲二大羣屬。第一型是合併有其他的先天性心臓病,另外一型則爲單獨存在型,在先天性心臓病當中,它約佔了0.4%,目前有5例是屬於第一型,皆經外科手術證實,其餘4例則屬於第二型。此9例經心導管左心室攝影有二尖瓣閉鎖不全症。以上這些兒童均無染色體的問題存在。男與女之比例爲1比2。第二型4例是由二尖瓣脫垂症所造成的,究竟是屬於先天性或後天性的迄今尚無定論。此文謹就M-型超音波圖的研究來鑑別出風濕性的或非風濕性的,進一步的證實工作,則需要外科醫師病理醫師,及生化專家的通力合作方可定案。

關鍵字

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並列摘要


From 1976 to 1982, nine cases of mitral insufficiency (MI) of non-rheumatic fever origin were studied at the Tri-Service General Hospital. These patients were classified into two types: the associated type and the isolated type. Five cases were associated with other cardiac defects: three cases with endocardial cushion defect and two cases with ventricular septal defect. Isolated MI was found in four cases. The diagnosis of mitral insufficiency was confirmed by left ventricular angiocardiography at the right anterior 30° oblique view. None of the nine cases had chromosomal abnormalities. Male to female ratio was 1:2. Mitral valve prolapse was almost always congenital in origin and usually not associated with other cardiac defects.

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