- 期刊
同性早熟與乳房過早發育女童之尿渣細胞學相
Urocytogram in Girls with Isosexual Precocity and Premature Thelarche
摘要
就經過長期臨床觀察證實診斷的8例同性早熟與7例乳房過早發育女童之尿液沈渣，施以細胞學檢查，結果發現：8例同性早熟女童之尿渣內，細胞總數較多，細胞個個分離，其中以中層細胞及表層細胞爲主，核濃縮指數較高；8例中7例之細胞成熟值大於36，7例之表層細胞指數大於5。從成熟值或表層細胞指數標準觀點，綜合判定8例同性早熟女童，在尿渣細胞學相，均呈動情激素效應。在此7例乳房過早發育女童之尿渣內，細胞總數較少，細胞易聚成羣，副基層細胞是主要的組成，核濃縮指數偏低成熟值均少於36，表層尿渣細胞指數均少於5，這些變化意味乳房過早發育女童之尿渣細胞學相，無動情激素效應。從上述結查可結論：細胞學相檢查術是簡便而容易實行，可做爲乳房發育過早症之初步篩檢工具。
關鍵字
無資料並列摘要
In eight girls with isosexual precocity, urocytographic studies revealed estrogen effects, judged by high superficial cell indices (more than five) and/or high maturation values (more than 36), Higher karyopyknotic indices, abundant cellularity and absence of cellular clustering were also noted in the urocytograms. On the other hand, in a group of seven girls with premature thelarche, none of the urocytograms revealed estrogen effects. Their superficjal cell indices and maturation values were less than fire and 36, respectively. Lower karyopyknotic indices scanty cellularity and presence of cellular clustering were also noted. The information obtained by means of the urocytogram examination is a useful screening test for differential diagnosis of isosexual precocity and premature development of the breast.