孕婦對德國麻疹病毒、巨細胞病毒、弓漿蟲及第Ⅰ、Ⅱ型單純性疱疹病毒感染之血清學調查

Survey of Infections Due to Rubella Virus, Toxoplasma Gondii, Cytomegalovirus and Type Ⅰ, Ⅱ Herpes Simplex Viruses in Pregnant Women

王志堅(Chih-Chien Wang) ； 朱夢麟(Mong-Ling Chu) ； 李淑華(Su-Hwa Lee) ； 李正華(Cheng-Hwa Lee) ； 陳繼詳(Chi-Hsian Chen) ； 顏兆熊(Chao-Shung Yen)

《Acta Paediatrica Sinica》 27卷1期 (1986/02) Pp. 34-39

摘要

以酵素免疫分析法，測定494位孕婦，在懷孕前三個月血清中抗德國麻疹病毒抗體、抗巨細胞病毒抗體、抗弓漿蟲抗體及抗單純性疱疹病毒第Ⅰ、Ⅱ型抗體。結果發現在494位孕婦中有351位(71%)血清中具有抗德國麻疹病毒抗體，425位元孕婦中有304位(72%)血清中具有抗巨細胞病毒抗體，338位元孕婦中有32位(9%)血清中具有抗弓漿蟲抗體，438位孕婦中有309位(71%)血清中具有抗單純性疱疹病毒第Ⅰ型抗體，420位孕婦中有245位(56%)血清中具有抗單純性疱疹病毒第Ⅱ型抗體。由此測定結果，我們可以了解目前懷孕年齡的婦女，對於易引起胎兒先天性感染之病原體的感受性。

並列摘要

By the use of an enzyme-linked immunosorbent assay (ELISA), anti-rubella virus antibody, anti-cytomegalovirus antibody, and anti-herpes simplex viruses type Ⅰ&Ⅱ antibodies were tested, in a group of sera from 494 pregnant women during first trimester. The results revealed that among 494 pregnant women, 351 (71%) had anti-rubella virus antibody, among 425 pregnant women, 304 (72%) had anti-cytomegalovirus antibody, among 338 pregnant women,32 (9%) had anti-toxoplasma gondii antibody and among 438 pregnant women, 309 (71%) had anti-herpes simplex virus type I antibody, among 420 pregnant women 245 (56%) had anti-herpes simplex virus type II antibody. From these results we can understand the prevalence of each virus or parasite infection in the past and the ratio of congenital or neonatal infection of babies at present.

並列關鍵字

rubella ； cytomegalovirus ； toxoplasma gondii ； herpes simplex virus ； enzyme-linked immunosorbent assay