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牛鏈球菌造成新生兒腦膜炎及敗血症:二病例報告

Streptococcus Bovis Meningitis and Sepsis in Neonates: Report of Two Cases

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摘要


牛鏈球菌(Streptococcus bovis)是屬於D羣牛鏈球菌之一員,D羣鏈球菌在人體感染以成人的心肌內膜炎與尿道發炎最常見,以前D羣健球茵在人體致病性一直被懷疑著,因為這羣細胞是人體消化道及會陰部的寄居者,一旦被從血液或脊髓培養出來時尚以為是污染所致。 在1968年以前從未見有被這羣細菌感染的報告,在此之後陸續有病例被報導出來,也逐漸引起醫界的注意,鏈球菌在新生兒感染以B羣最多見,而牛鏈球菌在新生兒感染是相當少見的,至於其所造成之腦膜炎更是只有少數病例被報導過,我們在此報告兩個在本院往院受牛鏈球菌感染,分別造成腦膜炎及敗血症的病例,並將其治療經過及經驗提出以供讀者共享,希望能引起對此等細菌之致病性的注意。

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並列摘要


Streptococcus bovis is a veterinary organism rarely previously reported in the neonatal infection. Two cases are presented of neonatal infection by this organism; one case manifested with nemingitis and the other, with sepsis, Seixure and respiratory distress were the symptoms found in these two babies, respectively Following adequate treatment, recovery was complete, and the infants enjoyed healthy lives post-discharge. S. bovis is always sensitive to penicillin, but resistant strain has been reported recently. It is reasonable to treat infant patients infected by this organism with a combined initial therapy of penicillin and aminoglycoside. After the minimal inhibitory concentration and minimal bactericidal concentration of antibiotic has been determined, penicillin or ampicillin can he used alone.

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