- 期刊
Unusual Clinical Features of Neonatal Anemia Due to Fetomaternal Transfusion
胎兒－母體輸血造成新生兒貧血的不尋常臨床表現
摘要
懷孕過程大約百分之五十會發生胎兒－母體輸血，且可造成嚴重的新生兒貧血。 一天大的女嬰，子宮內發育遲緩，由一名GIP1產婦生下，母體懷孕過程無任何出血合併症。嬰兒出生時呈現蒼白及呼吸淺快。實驗室檢查結果為嚴重貧血，（血紅素：4.8 gm/dl，血球溶積比：14.7%），網狀組織球增加，正成紅血細胞增加。直接型Coombs’試驗呈陰性反應。腦部超音波檢查正常。母親血液抹片以Kleihauer-Betke方法處理過後，呈現有胎兒紅血球。嬰兒的症狀於濃縮紅血球輸血後獲得改善。本文我們描述和討論此病例的不尋常臨床表現。對於不能預料的新生兒貧血，母親血液抹片以Kleihauer-Betke方法處理的檢查乃是必須的。
關鍵字
無資料並列摘要
Fetomaternal transfusion occurs in about 50 percent pregnancies. However, it can cause severe neonatal anemia at birth. A one-day-old baby girl, small for gestational age, was born to a GIPI woman without perinatal blood loss or obstetric complication. Pallor and mild tachypnea were noted after birth. Laboratory examination revealed severe anemia, (Hb: 4.8 gm/dl, Hct: 14.7%), reticulocytosis and normoblastemia. Direct coombs' test was negative. Brain echo examination was normal. Maternal peripheral blood smear stained with Kleihauer-Betke technique demonstrated presence of fetal cells. Following packed red blood cells transfusion, the baby's symptoms improved. The unusual clinical features were described and discussed. Kleihauer-Betke test should be performed in unexpected neonatal anemia after birth.