- 期刊
Endocarditis Due to Neisseria Sicca: Report of One Case
Neissera Sicca心內膜炎：一病例報告
摘要
由非致病性Neisseria菌所引的心內膜炎是一罕見但極為嚴重的感染性疾病。本報告描述一位罹患心室中膈缺損的小孩，得到了由Neisseria sicca所引起的傳染性心內膜炎。根據文獻的記載，在1993年以前，這類病例僅有十一例的報告；大多數病人先前有心臟疾病如先天性或風濕性心臟病，由於Neisseria sicca為人類口腔的常在菌，一般認為蛀牙、拔牙或口腔衛生不良是促進此病發生的重要因素。在臨床上，N.sicca心內膜炎亞急性發作，與由viridans streptococci所引起的心內膜炎不易區分，然而如果未能盡早診斷與治療，此病有極高比例的病人可能發生embolization的並發症。
並列摘要
Many species of the Neisseria, which are respiratory commensals in humans, have been regarded as being nonpathogenic or as causing disease in only immunocompromised hosts. We report a case in which Neisseria sicca was the cause of infective endocarditis in a child with a ventricular septal defect and review the literature on endocarditis due to N. sicca infection. Most of these patients had an underlying heart disease. Dental caries and poor oral hygiene may be two factors that predispose patients to the infection. N. sicca endocarditis usually results in a subacute onset of symptoms and, if not diagnosed early and treated, is associated with a high rate of embolic complications.