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甘草甜素對慢性C型肝炎血清生化值的臨床觀察

Clinical Observation of Stronger Neo-Minophagen C Decreased the Alanine Aminotransferase Levels of Non-Responders and Relapse's of Chronic Hepatitis C

摘要


慢性C型肝炎的標準治療是使用干擾素與抗病毒藥物(ribavirin),但是仍有部份患者治療後,無持續性反應,或治療發。文獻指出,長期接受靜脈注射甘草甜素(StrongerNe-Minophagen C,簡稱SNMC),可以預防肝硬化的發生,而且可以減少肝癌的發生率。因此我們自2005年1月起到2006年6月止,計有13位慢性C型肝炎患者,平均年齡60.1歲,使用SNMC點滴注射連續五天。治療前、治療後各測量肝功能ALT、AST值。本研究發現甘草甜素短程治療後,會降低慢性C型肝炎ALT值。

並列摘要


Interferon combined ribavirin therapy in chronic hepatitis C was a standard principle except non-responders or relapse's. Stronger Neo-Minophagen C (SNMC) is a potentially anti-inflammatory agent for chronic hepatitis C in Japan. The clinical trial that the serum levels of ALT(alanine aminotransferase) and AST (asparate aminotransferase) were observed for non-responders and relapse's of chronic hepatitis C patients treated by iv SNMC treatment. All thirteen patients included six non-responders, five relapses, and two acute exacerbation administered intravenous 3 amp of SNMC diluted in saline solution 100 cc per day, and slowly infusion for 5 days since Jan.2005 to Jun.2006. Result demonstrated that SNMC decreased the serum ALT levels of chronic hepatitis C.

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