Pogostemon Cablin Extract for Inhibiting Haemophilus Influenzae Adhesion

廣霍香萃取物抑制流感嗜血桿菌附著作用的實驗研究

蔡修賢(Hsiu-Hsien Tsai) ； 和禎診所(Ho-Jen Clinic)

《中西整合醫學雜誌》 17卷2期 (2015/06) Pp. 15-19

摘要

流感嗜血桿菌是藉由空氣中的飛沫或直接接觸分泌物而人傳人。流感嗜血桿菌是一種重要的定殖於上呼吸道粘膜的人類特定病原菌。流感嗜血桿菌對於人類細胞（例如：口咽細胞）之附著作用，被廣藿香植物的水萃取物所抑制。

關鍵字

廣藿香 ； 流感嗜血桿菌 ； 抗流感嗜血桿菌試驗

並列摘要

Haemophilus Influenzae are spread from person to person by airborne respiratory droplets or direct contact with secretions. Haemophilus Influenzaeare is an important human-specific pathogen colonizing the mucosa of the upper respiratory tract. The attachment of Haemophilus influenzae to human cells such as oropharyngeal cells, is inhibited by aqueous extract of Pogostemon cablin.

並列關鍵字

Pogostemon Cablin ； Haemophilus Influenza ； Anti- Haemophilus Influenzae Testing

參考文獻

Arne Forsgren, Kristian Riesbeck, and Håkan Janson: Protein D of Haemophilus influenzae: A Protective Nontypeable H. influenzae Antigen and a Carrier for Pneumococcal Conjugate Vaccines, Clinical Infectious Diseases 2008; 46:726–31.

Swords WE1, Ketterer MR, Shao J, Campbell CA, Weiser JN, Apicella MA: Binding of the non-typeable Haemophilus influenzae lipooligosaccharide to the PAF receptor initiates host cell signaling. Cell Microbiol 2001; 3(8):525-36.

Stenfors LE, Räisänen S: Abundant Attachment of Bacteria to Nasopharyngeal Epithelium in Otitis-Prone Children, Journal of Infectious Diseases 1992; 165:1148-1150.

Hsien-Chang Chang, Medicinal Herbs II, Holiday Publishing Co., Taipei, Taiwan, 1991; 67.

Woei-Song Kan: Pharmaceutical Botany, National Research Institute of Chinese Medicine, Taipei, Taiwan, 1971; 485.