高雄醫學院泌尿科自1978年1月至1982年12月5年間共治療了119例膀胱移行性上皮細胞癌患者,至中A型血型患者有38例,B型23例、AB型8例及O型50例,四組血型患者無論其臨床分期或病理級別在統計上並無顯著的差異;至於其5年存活率A型血型患者為40%,B型46%,AB型33.3%,O型僅有6.9%。由本研究顯示O型血型患者發生膀胱癌或膀胱癌惡性化的傾向並沒有比其他3種血型患者的機率高,但是O型血型患者其5年存活率較其他3種血型患者差,其真正原因仍有待作進一步研究。在119例中追踪時間超過5年的病例有67例,其中有21例追踪着,就其46例作統計分析。
A retrospective study was conducted on 119 patients with transitional cell carcinoma of the bladder. The frequencies of ABO blood groups among bladder cancer patients in this series correlated well with the frequencies found in the general population. Findings indicated that 38 cases (32%) were of blood group A, 23 cases (19.3%) of goups B, 8 cases (6.7%) of group AB and 50 cases (40.3%) of group O. No statistically significant difference occurred between pathological grading, clinical staging of tumors and blood group distributions. Of the 67 cases in which operations had occurred more than 5 years prior, 21 patients were lost to follow up. However, in the remaining 46 patients, patients in blood group O showed a poorer 5 year survival rate (6.9%) than those in group A, B and AB. Survival rates in the latter were 40%, 46.7% and 33.3% respectively. Although the findings indicated a statiscally significant difference between survival rates and blood groups (p<0.01), the relationship between blood groups and the prognosis of tumor requires future study and evaluation.