顱內腦膜瘤經常會引起腦瘤周圍水腫,但其原因仍眾說紛云,莫衷一是。我們收集38位病患,共39例病理證實之腦膜瘤,從電腦斷層判讀計算其腦水腫容積以作各種分析。病患中有27位女性,11位男性,年齡分佈於11歲到77歲,平均47.6歲。我們的研究發現腦瘤周圍水腫的嚴重性與手術前症狀期間長短,腫瘤位置和大小,以及腦皮質完整性的破壞有關。病理分類中的腦脊髓膜內皮細胞瘤型較易引起腦瘤周圍水腫。超顯微結構分析顯示腫瘤內,分泌作用的增加可能與腦瘤周圍水腫的發生有關。
We analyzed 38 patients with 39 meningiomas verified pathologically. The study included 27 females and 11 males. The ages of the patients on admission ranged from 11 to 77 years (averaged 47.6 years). The incidence of brain edema associated with meningiomas was 69%. The extent of peritumoral edema on the CT scans positively related to the duration of preoperative symptoms, the location and size of tumors, and breaching of the cortex by meningiomas. The meningotheliomatous meningiomas were frequently associated with significant brain edema. The ultrastructural features showed some relationship between increased secretory activity and the extent of peritumoral edema.