- 期刊
迴腸之發炎性類纖維息肉：病例報告
Ileal Inflammatory Fibroid Polyp: Case Report
摘要
發炎性類纖維息肉為一罕見之骨腸道息肉，其最常發在胃部，小腸次之，大腸最少；本病例是發生在迴腸，並且造成腸套疊及腸阻塞。至今為止，此種病灶之組織源性及疾病發生論尚無定論。 本病例的顯微鏡下觀察發現，其基本上是由在形態上與纖維芽胞相同的梭形或星形胞之增殖所組成；免疫組織化學染色發現增生的細胞對V imentin呈強烈反應外，並有局部小量散在性之細胞對S100蛋白呈陽性反應，而對上皮細胞膜抗原、第八因子相關抗原、平滑肌肌動絲及溶菌酵素皆呈陰性反應；因此，比較支持發炎性纖維息肉為纖維芽細胞源性的病灶。
關鍵字
無資料並列摘要
The inflammatory fibroid polyp is a rare, polypoid lesion in the gastrointestinal tract. It occurs in the stromach, small intestine, and large intestine in descending order of frequency. This case report shows an ileal inflammatory fibroid polyp that causes ileoileal intussusception. So far, the histogenesis and pathogenesis of these kinds of polyps are still uncertain. Under the microscopic examination, the lesion appears to be made up of spindleshaped or stellate cells that are morphologically identical to proliferating fibroblasts. Immunostaining results are strongly positive for vimentin and focally positive for S100 protein. However, epithelial membrane antigen, factor VIII R Ag, smooth muscle actin, and lysozyme test are all negative. This favors the view that the inflammatory fibroid polyp is fibroblastic in origin.