在分析26例的腦膜轉移中,我們發現磁振掃描之Gd-DTPA對比顯像最能提供診斷資料。其重要之表徵依序為(1)腦膜之顯影加強,(2)腦室內膜顯影加強,(3)腦室或蛛網膜下腔之板狀,結節,瘤狀增生,(4)顱內神經根之肥厚,(5)非原發性腦瘤所引起之腦室擴大。由文獻之回顧,原發性腦瘤所引起之脊髓蛛網膜下腔之轉移及由脊髓原發性膠質細胞瘤所引起之顱內蛛網膜下腔,腦室內之轉移甚為罕見。本文中,有3例為原發性腦瘤引起脊髓蛛網膜下腔轉移,有一例脊髓原發性膠質細胞瘤引發之顱內蛛網膜下腔轉移在此一併討論。
Twenty-six cases with leptomeningeal metastasis were analyzed and Gd-DTPA enhanced MR imaging was found to be the most useful tool for making the diagnosis. The important manifestations in order of frequency were: 1) leptomeningeal enhancement; 2) ependymal enhancement; 3) plaque, nodule or mass in the subarachnoid space or ventricles; 4) nerve root thickening; and 5) ventricular dilatation not related to the obstruction of the primary neoplasm. A review of the literature has shown that intracranial leptomeningeal metastasis from spinal cord astrocytoma are very rare. In our series, 3 cases with primary brain tumors developed spinal subarachnoid involvement. This paper also reviews 1 case with thoracic cord astrocytoma which developed multiple intracranial leptomeningeal metastasis.