Dimethylformamide-Induced Occupational Liver Injury - A Case Report

二甲基甲醯胺引起之肝傷害

黃志富(Jee-Fu Huang) ； 郭行道(Hsing-Tao Kuo) ； 何啟功(Chi-Kung Ho) ； 陳東榮(Tong-Jong Chen) ； 張文宇(Wen-Yu Chang)

《The Kaohsiung Journal of Medical Sciences》 14卷10期 (1998/10) Pp. 655-658

https://doi.org/10.6452/KJMS.199810.0655

摘要

二甲基甲醯胺為工業上被廣泛使用之有機溶劑。但經由呼吸道、皮膚及消化道的過度攝取常會導致肝傷害。我們報當亞例四十二歲男性因職業上過度暴露於二甲基甲醯胺而造成肝傷害之病例報告。病患除了有明顯的臨床病狀外，系列之肝功能檢查、職業暴露史及肝臟病理學檢查顯示此為一二甲基甲醯胺導致之急性肝傷害病例。

並列摘要

Dimethylformamide(DMF), a widely used industrial solvent, has been reported to induce subtle to clinically overt hepatotoxicity. Liver injury due to occupational exposure through inhalation and skin contact have been sporadically reported. We reported a 42-year-old male Taiwanese who developed progressive, intermittent abdominal pain for 6 months after working in a synthetic leather factory. Acute hepatitis episode occurred after working in an enclosed and poorly-ventilated workplace for one day. Based on occupational history, pathological examination and serial liver function examinations, the case was compatible with DMF-induced acute chemical hepatitis.

並列關鍵字

dimethylformamide ； hepatotoxicity