- 期刊
Bladder Wall Calcification after Intravesical Chemotherapy with Mitomycin C - a Case Report
絲裂黴素C(mitomycin C)膀胱灌注化學治療後造成膀胱壁鈣化：－病例報告
摘要
膀胱壁鈣化在臨床上十分罕見。我們在這將發表一個因絲裂黴素C膀胱灌注化學治療後造成膀胱壁鈣化的病例報告，同時回顧過去的研究來作討論。本病例是在接受絲裂黴素C治療三年後，因膀胱上皮性細胞癌復發接受經尿道內視鏡膀胱腫瘤切除手術時意外發現。病理報告證實惡性腫瘤復發，同時合併有鈣化之現象。在術後三個月的例行性膀光鏡追蹤依然可見膀胱鈣化之現象，且鈣化之位置主要位在之前經內視鏡切除之傷口。同時針對鈣化位置所做的切片檢查並沒有發現腫瘤之復發。據我們所知，本病例是第一個在接受絲黴素C膀胱灌注化學治療後，發生膀胱壁鈣化同時又合併有惡性腫瘤復發之病例。我們建議對於因絲裂黴素C膀胱灌注化學治療後造成的膀胱壁鈣化應做切片或切除之治療，以預防同時合併膀胱腫瘤復發之可能性。
關鍵字
無資料並列摘要
Bladder wall calcification has relatively few etiologies. We present such a case and review the literature to discuss it and the method for management. This case suffered from bladder wall calcification about 3 years after intravesical chemotherapy of mitomycin C. It was found accidentally during the transurethral resection of recurrent bladder tumor. The pathology confirmed the recurrence of transitional cell carcinoma combined with marked calcification. A repeat cystoscopy was done 3 months later. Massive calcified deposits in bladder wall especially in lesion of previous transurethral resection were still noted. Randomized biopsy showed dystrophic calcification without evidence of malignancy. We suggest that biopsy and /or resection ( if possible) is a reasonable approach to eliminate the possibility of invasive bladder cancer.