- 期刊
Eosinophilic Cystitis: Eight Cases Report and Literature Review
嗜伊紅性膀胱炎
摘要
從過去來看，嗜伊紅性膀胱炎是一種經由病理診斷，少見的嗜伊紅性球浸潤的膀胱發炎疾患。在過去儘管很多因素被認為是與這疾病有關，但其真正的原因仍不清楚。我們報導八位罹患嗜伊紅性膀胱炎的病人。全部病人皆接受完整病史，臨床表徵，放射線檢查，及治療反應的評估，並與其他文獻做比較。結果顯示最常見的症狀是血尿（七位病人），排尿困難（六位病人），頻尿（四位病人）和尿滯留（四位病人）。七位病人之尿液常規檢查顯示白血球增多但培養無結果。一位病人的放射線檢查發現膀胱腫塊和上泌尿道擴張。膀胱鏡檢查為每一個病人的主要診斷步驟，可發現類似腫塊的、水腫的、潰瘍的、及充血的黏膜病變。關於治療方面，所有的病人經由尿道做膀胱疾患的切片或切除作為首選步驟。然而當簡單的治療無法解決這個問題時，部份或全部膀胱切除應列為考慮。另外個別或合?給與抗組織胺，類固醇或抗生素可控制臨床症狀。在我們的病人中，只有一位有疾病復發的情形，但是在經過簡單的手術及藥物治療後即恢復，其餘的病人則治療效果佳。雖然我們的報導顯示很好的結果，但是長期追蹤是必須的。
關鍵字
無資料並列摘要
Historically, eosinophilic cystitis is a rare disorder of bladder inflammation with eosinophils infiltration diagnosed by pathologic examination. The etiology is unclear despite the past identification of many factors contributing to this disease. Eight patients with eosinophilic cystitis were reported. The intact history, clinical manifestation, radiological examination and response to therapy were all evaluated. The results showed that 7 patients developed hematuria,6 patients were with dysuria, 4 patients with frequency and 4 patients with urine retention. Seven patients had abnormal urinalysis but no positive finding in culture. Radiological findings revealed that one patient had bladder mass lesions and upper urinary tract dilation. Cystoscopic examination was performed in every patient and showed mass-like, edematous, ulcerative or hyperemic mucosa lesions. Cold-cup biopsy or transurethral resection of bladder lesions were all performed and could be the first priority to be considered. However, partial or total cystectomy should be taken into consideration when simple treatment failed to resolve this problem. Additionally, antihistamines, steroids or antibiotics are given to control the clinical symptoms. The results of these treatments were good except for one case who suffered from recurrence but recovered after simple operation and oral therapy. Although good results were found concerning treatment, long-term fol. low-up is necessary.