- 期刊
Modified Gunderson Conjunctival Flap Combined with an Oral Mucosal Graft to Treat an Intractable Corneal Lysis after Chemical Burn: A Case Report
利用改良式的甘德森結膜皮瓣合併口腔黏膜移植來治療因化學灼傷而引起的角膜溶解：病例報告
摘要
遭受嚴重的化學灼傷之後，持續的角膜溶解會對視力或眼球造成極大的威脅，層狀角膜整型術、角膜移植術和羊膜片移植術是最常用的治療方法。然而這些療法並不一定會使持續性的角膜溶解緩解下來。我們介紹另一種手術方法來處理角膜溶解的問題，使得眼球得以保留下來。本文描述一位36歲的男性其右眼遭受嚴重的鹼性化學性灼傷，在接受3次角膜移植術、一次輸狀幹細胞移植術、2次鞏膜片移植術及8次羊膜片移植術，其角膜還是一直持續性的溶解。為了避免造成眼球破裂，我們使用改良式的甘德森結膜皮瓣合併口腔黏膜移植術來治療病人，術後角膜溶解的現象停止，而病人的眼球才得以保留下來。由此顯示改良式的甘德森結膜皮瓣合併口腔黏膜移植是另一種簡單的手術方法可用來解決棘手的角膜溶解及伴隨而來的眼球破裂。
並列摘要
Following a severe chemical injury, persistent corneal melting presents as a threatening condition for loss of vision or the eyeball itself. Keratoplasty (both lamellar and penetrating) and amniotic membrane transplantation have been the usual modes of therapy. However, these may not halt the persistent melting process. We introduce here an alternative surgical procedure to resolve corneal melting and preserve the globe. This case concerns the right eye of a 36-year-old male who had suffered from severe ocular alkali chemical burns and sustained intractable corneal melting, despite receiving corneal transplants three times, a limbal stem cell transplantation once, a scleral graft twice, and amniotic membrane transplantation eight times. To circumvent the impending perforation, we performed a modified Gunderson conjunctival flap combined with an oral mucosal graft. The corneal melting was halted, and the eyeball was preserved. The combination of an oral mucosal graft to the modified Gunderson conjunctival flap provided an easy alternative to resolve a case of intractable corneal melting and impending perforation.