Evidence-based practice is a core competency of nursing. Evidence-based nursing development, evidence-based policy making, and quality of care in Taiwan are reaching the global standard. In this article, the development goals of four international evidence-based organizations have been introduced. This article was based on the JBI healthcare model to discuss the possibilities of evidence-based development, as well as the status of evidence synthesis, evidence knowledge transfer, and evidence implementation. Finally, I have made suggestions regarding evidence-based development and clinical implementation.