- 期刊
Fortified Juice Drink Improved Iron and Zinc Status of Schoolchildren
強化果汁改善學齡兒童體內鐵和鋅的狀態
摘要
菲律賓的兒童至今仍然有能量和微量營養素缺乏的問題。果汁是常吃的食物，因此可以當作營養強化的載體，來填補營養素的缺口。本篇研究的目的是測定一種新開發非碳酸強化果汁對學齡兒童體內鐵、鋅和營養狀況的影響。從貧血兒童中隨機抽出100位，再隨機分配至2組並採雙盲、安慰劑控制的試驗。第1組接受強化果汁，第2組接受非強化果汁。在嚴格監督下，每週5天，共進行10天。強化果汁添加的物質有維生素A、鋅、鐵、維生素C及離胺酸；非強化果汁只添加維生素C。所有兒童在介入之前已驅完蟲。介入前後利用標準化測量方試來評估血紅素、血漿鐵蛋白和鋅、體重及身高，另外也蒐集了2 天的24 小時飲食回憶記錄。試驗結束時，強化組（100%降至13%）與非強化組（100%降至40%）的貧血盛行率均顯著下降。強化組的血漿鐵蛋白平均值顯著增加了20 μg/dL，從試驗前的83.9 μg/dL增加至103.9 μg/dL，但非強化組的數值則和試驗前相同; 所有兒童的身高、體重均有顯著增加。強化果汁可以有效地降低貧血的盛行並且改善兒童體內的鋅狀態。
並列摘要
Energy and micronutrient deficiency remain prevalent among Filipino children. Juice drinks are commonly consumed and could be a viable vehicle for fortification to supplement the nutrient gap. This study determined the effects of a newly developed non-carbonated fortified juice drink on the iron, zinc and nutritional status of schoolchildren. One hundred randomly selected anemic children were randomly allocated into two groups in a doubly-masked placebo controlled manner: Group 1 received the fortified juice, Group 2 received the nonfortified juice for 100 days, five days a week under strict supervision. The juice drink was fortified with vitamin A, zinc, iron, vitamin C and lysine. The non-fortified juice was fortified only with vitamin C. All children were dewormed prior to the intervention. Hemoglobin, plasma ferritin and plasma zinc, weight and height were assessed using standard methods before and after intervention. A two-day 24-hour food recall was also collected. The basal prevalence of anemia was significantly reduced in both the fortified group (100% to 13%) and the non-fortified group (100% to 40%) at endline. The mean plasma ferritin levels were similar in both groups at baseline and endline. At endline, mean plasma zinc in the fortified group has significantly increased by 20 μg/dL from a baseline value of 83.9 μg/dL to 103.9 μg/dL, while the non-fortified group remained at similar levels with baseline. Basal weight and height significantly increased among all children at endline. The fortified juice drink was effective in reducing the prevalence of anemia and improved the zinc status of children.