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Introduction: Hypertension is not common in infants and young children. The etiology of hypertension in this age group may be different from older children and young adults. Hypertension may be associated with intussusception in young children. Case Report: A previously healthy 17-month-old, ill-appearing and dehydrated girl was brought to the emergency department with fever and vomiting for three days. The vomiting was non-bilious and non-projectile. Her temperature was 103°F, heart rate was 126/min, respiratory rate was 32/min, oxygen saturation 98% and blood pressure 122/77 mmHg. She had dry mucous membranes. The abdomen was soft with mild tenderness in the left upper quadrant and no palpable masses. She was diagnosed with ileocolic intussusception. Conclusion: Intussusception should be considered a diagnostic possibility in infants who have a history of vomiting and in whom lethargy and hypertension are the presenting features. This case report demonstrates the importance of measuring blood pressure in ill-appearing children.

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