Introduction: Parastomal hernias are a common complication of ileostomy and colostomy creation. Most are managed non-operatively, but some require surgery because of progressive symptoms and obstruction. Porcine urinary bladder matrix (UBM), utilized in many hernia applications, serves as an effective biologicallyderived extracellular matrix scaffold and facilitates a favorable remodeling response with restoration of site-appropriate tissue. Case Series: Herein, eight cases are presented which describe four different techniques of parastomal hernia repair utilizing porcine UBM. In four cases, repair was performed through open laparotomy; the remaining four were performed laparoscopically. All repairs were reinforced with porcine UBM. Median duration of follow-up is 23 months. Conclusion: Surgeons may safely employ open and laparoscopic techniques for successful repair of parastomal hernias. In this series of eight cases, repairs with porcine UBM devices have proven durable at two years of follow-up and may serve as an alternative to synthetic mesh.