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The Effects of Diets on Plasma Lipids and Lipoprotein Phospholipids in Man
不同飲食對人類血脂肪及血脂蛋白中磷脂質的影響
摘要
39位健康男性，在食用一般美式飲食（38%總脂肪、18%飽和脂肪、10%多元不飽和脂肪、10%單元不飽和脂肪、500毫克膽固醇）10星期後，分為三組，一組繼續上述飲食，另一組改為加強單元不飽脂肪的飲食（38%總脂肪、10%飽和脂肪、10%多元不飽和脂肪、18%單元不飽和脂肪、250毫克膽固醇），最後一組則改為美國心臟病學會建議第一階段飲食（30%總脂肪、10%飽和脂肪、10%多元不飽和脂肪、10%單元不飽和脂肪、250毫克膽固醇），每一組均食用10星期。 血脂肪及血脂蛋白磷脂質測定結果顯示：血清總膽固醇、三酸甘油脂及低密度脂蛋白膽固醇在第一階段飲食及加強單元不飽和飲食均下降。空腹的血脂蛋白的磷脂質在不同的飲食類別中沒有差異，在加強單元不飽和脂肪飲食中，飯後低密度脂蛋白磷脂質明顯低於一般美式飲食，而高密度脂蛋白磷脂質則增加，比較所有食用一般美式飲食的血脂蛋白磷脂質，發現極低密度脂蛋白中磷脂質含量在飯後均明顯升高，但高密度脂蛋白脂質並未增加。
關鍵字
無資料並列摘要
Thirty nine healthy males were subjected an average America1n Diet (AD) of 38% fat (18% Saturated fat (SF), 10% Polyunsaturated fat(PF), 10% Monounsaturated fat (MF) and 500mg/day cholesterol for 10 weeks and then they were divided into 3 groups: one group continued on consuming the AD; the second group switched to a monounsaturated fat enriched diet (MD) of 38% fat (10%SF, 10%PF, 18%MF) and 250mg/day cholesterol; and the third group switched to the American Heart Association Step 1 Diet of 30% fat (10%SF, 10%PF, 10%MF) and 250mg/day cholesterol. Each group consumed these diets for another 10 weeks. Plasma lipids and lipoprotein phospholipids (PLs) were measured. The consumption of both the Step 1 Diet and MD reduced total plasma cholesterol, triglyceride and LDL-cholesterol. Fasting lipoprotein PLs were not significantly different among the three groups. For postprandial lipoprotein PLs, there were significant decrease in LDL-PLs and increase in HDL-PLs in the MD group compared with AD group. When postprandial PLs were compared with fasting PLs in all subjects during the AD period, postprandial VLDL-PLs increased significantly. Unlike data from other studies, postprandial HDL-PLs did not increase on the AD.