Clinical Trial of Glipizide on Thirty-one Maturity-onset Diabetes

Glipizide用於治療三十一位成年型糖尿病病人之臨床評價

林宏達(H. D. Lin)

《Journal of Medical Sciences》 2卷2期 (1977/12) Pp. 535-539

摘要

Glipizide是一種新的口服(月黃)基脲類降血糖藥物。以每日5～15毫克來治療三十一位成年型糖尿病人，治療期限為1～9個月，在九個較嚴重的糖尿病人中，三個糖尿病獲得改善，而另外二十二個較輕糖尿病病人也都得到有效的控制。糖尿病病人對此藥之耐受性很好，未曾發生低血糖反應。本臨床試驗證實了Glipizide的降血糖效力及其安全性。

並列摘要

Thirty-one maturity-onset diabetic patients were treated with 5.0-15.0 mg glipizide daily for 1-9 months. Three of the nine severe diabets showed improvement after switching to glipizide and all the twenty-two milder diabetes responded to this new agent. Tolerence of the drug was good, no hypoglycemic reaction occurred. The hypoglycemic property and safety of this new oral hypoglycemic drug were confirmed by this triaI.