- 期刊
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直腸單一潰瘍徵候群－病例報告
Solitary Rectal Ulcer Syndrome: A Case Report
摘要
直腸單一潰瘍（solitary ulcer of the rectum）是一極少見的病例；具有明顯的臨床特徵，好發於年青人，尤其是有直腸流血病史的年青人。單一潰瘍徵候群（solitary ulcer syndrome）88%發生在直腸部位，其中以直屬黏膜的前壁及前外側壁最多見約佔65%。排便時恥骨直腸肌（puborectalis muscle）的不協調以及排便刮起的磨擦，導致潰瘍的形成。典型的組織變化，使病理醫師能正確的診斷出此一疾病。本文所報告之此一罕見病例，是一位20歲的男性青年，主訴大量直腸流血並且排泄含有大量黏液的大便，經直腸鏡切片檢查，證實為直腸單一潰瘍徵候群，特此提出討論其致病機轉及組織病理變化。
並列摘要
Solitary rectal ulcer is a rare disease with only scarcity of reports appeared in the literature. The common clinical features include bleeding and passage of mucus on defecation, increasing frequency of defecation, and anal and lower abdominal pain. Although most of the cases are diagnosed according to the clinical history and symptoms of the leison, classical histologic changes have been demonstrated to be the major tool for making accurate diagnosis. Solitary, and occasionally multiple ulcers occur predominantly at the anterior and anterolateral aspects of the rectum. The course is chronic and the disease is extraordinarily resistant to treatment recurring after local resection. The etiology is still unclear. One typical case of solitary rectal ulcer syndrome is presented in this article. The possible pathogenesis and histologic changes are also discussed.