腺瘤性息肉合併早期膽囊癌－病例報告及文獻回顧

Early Carcinoma of the Gallbladder Arising in an Adenomatous Polyp: Report of a Case and Review of the Literatures

羅杰(Chiech Lo) ； 袁至仁(Jyh-Ren Yuan) ； 李天俠(Tian-Shya Lii) ； 沈景發(Jiing-Fa Sheen)

《Journal of Medical Sciences》 12卷6期 (1992/06) Pp. 432-439

摘要

原發性膽囊癌為一種較少見、不易診斷及預後差的惡性腫瘤，約佔所有膽囊切除病例的1%；平均存活率為6個月。縱使實施較廣泛手術，五年存活率仍小於5%。早期膽囊癌可藉著膽囊切除手術根治，其三年存活率高達100%。因而早期診斷極為重要。本病例報告一位57歲男性，因多發性膽囊結石及腺瘤性息肉合併局部原位癌，而接受單純膽囊切除術。手術後門診追蹤迄今已逾6個月情況良好。因早期膽囊癌非常罕見，故對其臨床、病理提出討論及相關性文獻之回顧。

關鍵字

膽囊癌 ； 腺瘤性息肉 ； 化生 ； 異常變化 ； 原位癌

並列摘要

Gallbladder cancer is an uncommon neoplasm, acounting for about 1% of all surgically removed gallbladder and associated with a poor prognosis and a late diagnosis. The median survival, from diagnosis is 6 months. the 5-year survival in most series in less thna 5% no matter how it is treated surgically. early carcinoma of the galbladder may be cured by cholecystectomy. The 3-year survival rate is 100%. So it is important of early diagnosis at a stage amenable to surgical excision. We herein, reported a case of 57-year-old man with multiple gallbladder stones and adenocarcinoma in situ arrising in an adenomatous polyp of the gallbladder who underwent simple cholecystectomy and follow-up in good condition for half year. Early carcinoma of the gallbladder in this category is very rare, so clinical and pathologic problems posed by this lesion and discussed with a brief survey of the literature.

並列關鍵字

Gallbladder carcinoma ； adenomatous polyp ； Metaplasia ； Dysplasia ； carcinoma in situ