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Central Precocious Puberty in a Child with the Suprasellar Arachnoid Cyst
並列摘要
Central or true precocious puberty occurs as a result of the premature release of luteinizing hormone releasing hormone (LHRH) from the hypothalamus. The LHRH stimulates the secretion of pituitary gonadotropins. Cerebral arachnoid cysts are rare causes of precocious puberty. We present a case of precocious puberty with a suprasellar arachnoid cyst. A 9-year-old boy presented with the appearance of secondary sexual characteristics for 1 year. Physical examination of genitalia revealed pubic hair, elongated penis and enlarged testis (about Tanner stage IV). An LHRH test revealed high levels of LH. The bone age of the left wrist was approximately that of a 13- or 14-yearold boy. Magnetic resonance image (MRI) of the brain revealed the presence of a third ventrically-oriented cystic lesion. The patient received the Leuplin depot (LHRH analog) treatment to block the development of puberty and increase adult height. Therefore, early detection of precocious puberty is important. Early diagnosis and treatment can minimize the physical and psychosocial problems and enhance the quality of life for patients with this condition.